Unveiling the potential of HS-1793: a review of its anticancer properties and therapeutic promise

  • Xavier Capó
  • , Manuel Jiménez-Garcia
  • , Farukh Sharopov
  • , Patrick Valere Tsouh Fokou
  • , Miquel Martorell
  • , Afaf Ahmed Aldahish
  • , Raffaele Pezzani
  • , Javad Sharifi-Rad
  • , Daniela Calina

Producción científica: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

1 Cita (Scopus)

Resumen

HS-1793 is a novel derivative of resveratrol, a compound known for its numerous beneficial effects, including anticancer activity, anti-inflammatory response, antimicrobial, antiaging, anti-cardiovascular disease activity, neuroprotective activity, etc. Despite its wide and interesting properties, resveratrol suffers from a crucial flaw because it is low bioavailable. For this reason, many other derivatives were explored and among them, HS-1793 has caught the attention of researchers. HS-1793 is a synthetic derivative of resveratrol discovered in 2007 that has been shown to have anti-cancer and anti-inflammatory properties. In addition, the compound showed a positive profile in metabolic processes, with adequate pharmacokinetics and pharmacodynamics. This review highlights current research on HS-1793, evaluating in vitro and in vivo works and lays the foundation for novel explorative trials in human diseases.

Idioma originalInglés
Páginas (desde-hasta)2301-2311
Número de páginas11
PublicaciónFuture Medicinal Chemistry
Volumen16
N.º21
DOI
EstadoPublicada - 2024

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