Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health

Bahare Salehi; Laura Machin; Lianet Monzote; Javad Sharifi-Rad; Shahira M. Ezzat; Mohamed A. Salem; Rana M. Merghany; Nihal M. El Mahdy; Ceyda Sibel Klllç; Oksana Sytar; Mehdi Sharifi-Rad; Farukh Sharopov; Natália Martins; Miquel Martorell; William C. Cho

doi:10.1021/acsomega.0c01818

Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health

Bahare Salehi
, Laura Machin
, Lianet Monzote
, Javad Sharifi-Rad
, Shahira M. Ezzat
, Mohamed A. Salem
, Rana M. Merghany
, Nihal M. El Mahdy
, Ceyda Sibel Klllç
, Oksana Sytar
, Mehdi Sharifi-Rad
, Farukh Sharopov
, Natália Martins
, Miquel Martorell
, William C. Cho

Bam University of Medical Sciences
University of Havana
Instituto de Medicina Tropical Pedro Kouri
Shahid Beheshti University of Medical Sciences
Cairo University
October University for Modern Sciences and Arts
Menoufia University
National Research Center
Ankara University
Kyiv National Taras Shevchenko University
Slovak University of Agriculture in Nitra
Kerman University of Medical Sciences
Avicenna Tajik State Medical University
University of Porto
Universidad de Concepción
Queen Elizabeth Hospital Hong Kong

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

601 Citas (Scopus)

Resumen

Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.

Idioma original	Inglés
Páginas (desde-hasta)	11849-11872
Número de páginas	24
Publicación	ACS Omega
Volumen	5
N.º	20
DOI	https://doi.org/10.1021/acsomega.0c01818
Estado	Publicada - 26 may. 2020
Publicado de forma externa	Sí

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Salehi, B., Machin, L., Monzote, L., Sharifi-Rad, J., Ezzat, S. M., Salem, M. A., Merghany, R. M., El Mahdy, N. M., Klllç, C. S., Sytar, O., Sharifi-Rad, M., Sharopov, F., Martins, N., Martorell, M., & Cho, W. C. (2020). Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health. ACS Omega, 5(20), 11849-11872. https://doi.org/10.1021/acsomega.0c01818

@article{f59e736ac695446a8cc99ff2b0490f41,

title = "Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health",

abstract = "Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.",

author = "Bahare Salehi and Laura Machin and Lianet Monzote and Javad Sharifi-Rad and Ezzat, \{Shahira M.\} and Salem, \{Mohamed A.\} and Merghany, \{Rana M.\} and \{El Mahdy\}, \{Nihal M.\} and Klll{\c c}, \{Ceyda Sibel\} and Oksana Sytar and Mehdi Sharifi-Rad and Farukh Sharopov and Nat{\'a}lia Martins and Miquel Martorell and Cho, \{William C.\}",

note = "Publisher Copyright: Copyright {\textcopyright} 2020 American Chemical Society.",

year = "2020",

month = may,

day = "26",

doi = "10.1021/acsomega.0c01818",

language = "Ingl{\'e}s",

volume = "5",

pages = "11849--11872",

journal = "ACS Omega",

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publisher = "American Chemical Society",

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T1 - Therapeutic Potential of Quercetin

T2 - New Insights and Perspectives for Human Health

AU - Salehi, Bahare

AU - Machin, Laura

AU - Monzote, Lianet

AU - Sharifi-Rad, Javad

AU - Ezzat, Shahira M.

AU - Salem, Mohamed A.

AU - Merghany, Rana M.

AU - El Mahdy, Nihal M.

AU - Klllç, Ceyda Sibel

AU - Sytar, Oksana

AU - Sharifi-Rad, Mehdi

AU - Sharopov, Farukh

AU - Martins, Natália

AU - Martorell, Miquel

AU - Cho, William C.

PY - 2020/5/26

Y1 - 2020/5/26

N2 - Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.

AB - Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.

UR - https://www.scopus.com/pages/publications/85085662281

U2 - 10.1021/acsomega.0c01818

DO - 10.1021/acsomega.0c01818

M3 - Artículo

AN - SCOPUS:85085662281

SN - 2470-1343

VL - 5

SP - 11849

EP - 11872

JO - ACS Omega

JF - ACS Omega

IS - 20

ER -

Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health

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