TY - JOUR
T1 - Therapeutic Potential of Quercetin
T2 - New Insights and Perspectives for Human Health
AU - Salehi, Bahare
AU - Machin, Laura
AU - Monzote, Lianet
AU - Sharifi-Rad, Javad
AU - Ezzat, Shahira M.
AU - Salem, Mohamed A.
AU - Merghany, Rana M.
AU - El Mahdy, Nihal M.
AU - Klllç, Ceyda Sibel
AU - Sytar, Oksana
AU - Sharifi-Rad, Mehdi
AU - Sharopov, Farukh
AU - Martins, Natália
AU - Martorell, Miquel
AU - Cho, William C.
N1 - Publisher Copyright:
Copyright © 2020 American Chemical Society.
PY - 2020/5/26
Y1 - 2020/5/26
N2 - Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.
AB - Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.
UR - https://www.scopus.com/pages/publications/85085662281
U2 - 10.1021/acsomega.0c01818
DO - 10.1021/acsomega.0c01818
M3 - Artículo
AN - SCOPUS:85085662281
SN - 2470-1343
VL - 5
SP - 11849
EP - 11872
JO - ACS Omega
JF - ACS Omega
IS - 20
ER -