The therapeutic potential of the labdane diterpenoid forskolin

Bahare Salehi; Mariola Staniak; Katarzyna Czopek; Anna Stepień; Kamal Dua; Ridhima Wadhwa; Dinesh Kumar Chellappan; Oksana Sytar; Marian Brestic; Namrata Ganesh Bhat; Nanjangud Venkatesh Anil Kumar; María del Mar Contreras; Farukh Sharopov; William C. Cho; Javad Sharifi-Rad

doi:10.3390/app9194089

The therapeutic potential of the labdane diterpenoid forskolin

Bahare Salehi
, Mariola Staniak
, Katarzyna Czopek
, Anna Stepień
, Kamal Dua
, Ridhima Wadhwa
, Dinesh Kumar Chellappan
, Oksana Sytar
, Marian Brestic
, Namrata Ganesh Bhat
, Nanjangud Venkatesh Anil Kumar
, María del Mar Contreras
, Farukh Sharopov
, William C. Cho
, Javad Sharifi-Rad

Producción científica: Contribución a una revista › Artículo de revisión › revisión exhaustiva

33 Citas (Scopus)

Resumen

Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy.

Idioma original	Inglés
Número de artículo	4089
Publicación	Applied Sciences (Switzerland)
Volumen	9
N.º	19
DOI	https://doi.org/10.3390/app9194089
Estado	Publicada - 1 oct. 2019
Publicado de forma externa	Sí

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Acceder al documento

10.3390/app9194089

Otros archivos y enlaces

Enlace a la publicación en Scopus

Citar esto

Salehi, B., Staniak, M., Czopek, K., Stepień, A., Dua, K., Wadhwa, R., Chellappan, D. K., Sytar, O., Brestic, M., Bhat, N. G., Kumar, N. V. A., Contreras, M. D. M., Sharopov, F., Cho, W. C., & Sharifi-Rad, J. (2019). The therapeutic potential of the labdane diterpenoid forskolin. Applied Sciences (Switzerland), 9(19), Artículo 4089. https://doi.org/10.3390/app9194089

@article{83ef471bc81f4793acc65fbf2e58a936,

title = "The therapeutic potential of the labdane diterpenoid forskolin",

abstract = "Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy.",

keywords = "CAMP pathway, Coleus forskohlii, Forskolin, Plant secondary metabolites",

author = "Bahare Salehi and Mariola Staniak and Katarzyna Czopek and Anna Stepie{\'n} and Kamal Dua and Ridhima Wadhwa and Chellappan, \{Dinesh Kumar\} and Oksana Sytar and Marian Brestic and Bhat, \{Namrata Ganesh\} and Kumar, \{Nanjangud Venkatesh Anil\} and Contreras, \{Mar{\'i}a del Mar\} and Farukh Sharopov and Cho, \{William C.\} and Javad Sharifi-Rad",

note = "Publisher Copyright: {\textcopyright} 2019 by the authors.",

year = "2019",

month = oct,

day = "1",

doi = "10.3390/app9194089",

language = "Ingl{\'e}s",

volume = "9",

journal = "Applied Sciences (Switzerland)",

issn = "2076-3417",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "19",

}

TY - JOUR

T1 - The therapeutic potential of the labdane diterpenoid forskolin

AU - Salehi, Bahare

AU - Staniak, Mariola

AU - Czopek, Katarzyna

AU - Stepień, Anna

AU - Dua, Kamal

AU - Wadhwa, Ridhima

AU - Chellappan, Dinesh Kumar

AU - Sytar, Oksana

AU - Brestic, Marian

AU - Bhat, Namrata Ganesh

AU - Kumar, Nanjangud Venkatesh Anil

AU - Contreras, María del Mar

AU - Sharopov, Farukh

AU - Cho, William C.

AU - Sharifi-Rad, Javad

PY - 2019/10/1

Y1 - 2019/10/1

N2 - Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy.

AB - Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy.

KW - CAMP pathway

KW - Coleus forskohlii

KW - Forskolin

KW - Plant secondary metabolites

UR - https://www.scopus.com/pages/publications/85073297648

U2 - 10.3390/app9194089

DO - 10.3390/app9194089

M3 - Artículo de revisión

AN - SCOPUS:85073297648

SN - 2076-3417

VL - 9

JO - Applied Sciences (Switzerland)

JF - Applied Sciences (Switzerland)

IS - 19

M1 - 4089

ER -

The therapeutic potential of the labdane diterpenoid forskolin

Resumen

ODS de las Naciones Unidas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto