TY - JOUR
T1 - Stevia rebaudiana Bertoni bioactive effects
T2 - From in vivo to clinical trials towards future therapeutic approaches
AU - Salehi, Bahare
AU - López, Maria Dolores
AU - Martínez-López, Sara
AU - Victoriano, Montserrat
AU - Sharifi-Rad, Javad
AU - Martorell, Miquel
AU - F. Rodrigues, Célia
AU - Martins, Natália
N1 - Publisher Copyright:
© 2019 John Wiley & Sons, Ltd.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Stevia rebaudiana Bertoni, a plant from South America and indigenous of Paraguay, has shown several biological effects and healthy properties, although it is especially used in South America and some Asiatic regions. In addition, it is a natural sweetener, almost 300 times sweeter than sucrose, being attributed to its phytoconstituents prominent antioxidant, antimicrobial, antidiabetic (antihyperglycemic, insulinotropic, and glucagonostatic), antiplatelet, anticariogenic, and antitumor effects. In this sense, this work aims to provide an extensive overview on the historical practices of stevia and its effects in human health based on its chemical composition and applications for both food and pharmaceutical industries.
AB - Stevia rebaudiana Bertoni, a plant from South America and indigenous of Paraguay, has shown several biological effects and healthy properties, although it is especially used in South America and some Asiatic regions. In addition, it is a natural sweetener, almost 300 times sweeter than sucrose, being attributed to its phytoconstituents prominent antioxidant, antimicrobial, antidiabetic (antihyperglycemic, insulinotropic, and glucagonostatic), antiplatelet, anticariogenic, and antitumor effects. In this sense, this work aims to provide an extensive overview on the historical practices of stevia and its effects in human health based on its chemical composition and applications for both food and pharmaceutical industries.
KW - Stevia rebaudiana Bertoni
KW - food-derived applications
KW - health promotion
KW - phytopharmacological potential
UR - https://www.scopus.com/pages/publications/85070830942
U2 - 10.1002/ptr.6478
DO - 10.1002/ptr.6478
M3 - Artículo de revisión
C2 - 31423662
AN - SCOPUS:85070830942
SN - 0951-418X
VL - 33
SP - 2904
EP - 2917
JO - Phytotherapy Research
JF - Phytotherapy Research
IS - 11
ER -
