TY - JOUR
T1 - Phytochemicals in Helicobacter pylori infections
T2 - What are we doing now?
AU - Salehi, Bahare
AU - Sharopov, Farukh
AU - Martorell, Miquel
AU - Rajkovic, Jovana
AU - Ademiluyi, Adedayo Oluwaseun
AU - Sharifi-Rad, Mehdi
AU - Fokou, Patrick Valere Tsouh
AU - Martins, Natália
AU - Iriti, Marcello
AU - Sharifi-Rad, Javad
N1 - Publisher Copyright:
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2018/8/10
Y1 - 2018/8/10
N2 - In this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts and isolated bioactive compounds with anti-H. pylori activity are also critically discussed. Lastly, special attention was also given to plant extracts with urease inhibitory effects, with emphasis on involved modes of action.
AB - In this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts and isolated bioactive compounds with anti-H. pylori activity are also critically discussed. Lastly, special attention was also given to plant extracts with urease inhibitory effects, with emphasis on involved modes of action.
KW - Anti-urease activity
KW - Helicobacter pylori
KW - In vitro/in vivo findings
KW - Opportunistic colonization
KW - Phytopharmacology
KW - Plant products
UR - https://www.scopus.com/pages/publications/85052079704
U2 - 10.3390/ijms19082361
DO - 10.3390/ijms19082361
M3 - Artículo de revisión
C2 - 30103451
AN - SCOPUS:85052079704
SN - 1661-6596
VL - 19
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
IS - 8
M1 - 2361
ER -