TY - JOUR
T1 - Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder
AU - Cruz-Martins, Natália
AU - Quispe, Cristina
AU - Kirkin, Celale
AU - Şenol, Ezgi
AU - Zuluǧ, Asli
AU - Özçelik, Beraat
AU - Ademiluyi, Adedayo O.
AU - Oyeniran, Olubukola Helen
AU - Semwal, Prabhakar
AU - Kumar, Manoj
AU - Sharopov, Farukh
AU - López, Victor
AU - Les, Francisco
AU - Bagiu, Iulia Cristina
AU - Butnariu, Monica
AU - Sharifi-Rad, Javad
AU - Alshehri, Mohammed M.
AU - Cho, William C.
N1 - Publisher Copyright:
© 2021 Natália Cruz-Martins et al.
PY - 2021
Y1 - 2021
N2 - Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules.
AB - Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules.
UR - https://www.scopus.com/pages/publications/85114610989
U2 - 10.1155/2021/1131280
DO - 10.1155/2021/1131280
M3 - Artículo de revisión
C2 - 34471461
AN - SCOPUS:85114610989
SN - 1942-0900
VL - 2021
JO - Oxidative Medicine and Cellular Longevity
JF - Oxidative Medicine and Cellular Longevity
M1 - 1131280
ER -