TY - JOUR
T1 - Obesity is associated with a higher prevalence of musculoskeletal pain in middle-aged women
AU - for the Collaborative Group for Research of the Climacteric in Latin America (REDLINC)
AU - Blümel, Juan Enrique
AU - Arteaga, Eugenio
AU - Mezones-Holguín, Edward
AU - Zúñiga, María Cristina
AU - Witis, Silvina
AU - Vallejo, María Soledad
AU - Tserotas, Konstantino
AU - Sánchez, Hugo
AU - Onatra, William
AU - Ojeda, Eliana
AU - Mostajo, Desiree
AU - Monterrosa, Alvaro
AU - Lima, Selva
AU - Martino, Mabel
AU - Hernández-Bueno, Jose Alberto
AU - Gómez, Gustavo
AU - Espinoza, María Teresa
AU - Flores, Daniel
AU - Chedraui, Peter
AU - Calle, Andrés
AU - Bravo, Luz María
AU - Benítez, Zully
AU - Bencosme, Ascanio
AU - Barón, Germán
N1 - Publisher Copyright:
© 2017 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017/5/4
Y1 - 2017/5/4
N2 - Musculoskeletal pain (MSP) has been recently linked with high plasma leptin levels. Our objective was to study if obese women, who have higher leptin levels, could have a higher frequency of MSP. We studied 6079 Latin-American women, 40–59 years old. Their epidemiological data were recorded and the Menopause Rating Scale (MRS), Golberg Anxiety and Depression Scale and Insomnia Scale were applied. MSP was defined as a score ≥2 on MRS11. Women with MSP were slightly older, had fewer years of schooling and were more sedentary. They also complained of more severe menopausal symptoms (29.2% versus. 4.4%, p < 0.0001). Furthermore, they had a higher abdominal perimeter (87.2 ± 12.0 cm versus 84.6 ± 11.6 cm, p < 0.0001) and a higher prevalence of obesity (23.1% versus 15.2%, p < 0.0001). Compared to normal weight women, those with low body weight (IMC <18.5) showed a lower risk of MSP (OR 0.71; 95%CI, 0.42–1.17), overweight women had a higher risk (OR 1.64; 95%CI, 1.44–1.87) and obese women the highest risk (OR 2.06; 95%CI, 1.76–2.40). Logistic regression analysis showed that obesity is independently associated to MSP (OR 1.34; 95%CI, 1.16–1.55). We conclude that obesity is one identifiable risk factor for MSP in middle-aged women.
AB - Musculoskeletal pain (MSP) has been recently linked with high plasma leptin levels. Our objective was to study if obese women, who have higher leptin levels, could have a higher frequency of MSP. We studied 6079 Latin-American women, 40–59 years old. Their epidemiological data were recorded and the Menopause Rating Scale (MRS), Golberg Anxiety and Depression Scale and Insomnia Scale were applied. MSP was defined as a score ≥2 on MRS11. Women with MSP were slightly older, had fewer years of schooling and were more sedentary. They also complained of more severe menopausal symptoms (29.2% versus. 4.4%, p < 0.0001). Furthermore, they had a higher abdominal perimeter (87.2 ± 12.0 cm versus 84.6 ± 11.6 cm, p < 0.0001) and a higher prevalence of obesity (23.1% versus 15.2%, p < 0.0001). Compared to normal weight women, those with low body weight (IMC <18.5) showed a lower risk of MSP (OR 0.71; 95%CI, 0.42–1.17), overweight women had a higher risk (OR 1.64; 95%CI, 1.44–1.87) and obese women the highest risk (OR 2.06; 95%CI, 1.76–2.40). Logistic regression analysis showed that obesity is independently associated to MSP (OR 1.34; 95%CI, 1.16–1.55). We conclude that obesity is one identifiable risk factor for MSP in middle-aged women.
KW - Leptin
KW - menopause
KW - middle-aged women
KW - obesity
KW - pain
UR - https://www.scopus.com/pages/publications/85010633309
U2 - 10.1080/09513590.2016.1269741
DO - 10.1080/09513590.2016.1269741
M3 - Artículo
C2 - 28084176
AN - SCOPUS:85010633309
SN - 0951-3590
VL - 33
SP - 378
EP - 382
JO - Gynecological Endocrinology
JF - Gynecological Endocrinology
IS - 5
ER -
