TY - JOUR
T1 - Nutraceutical Profiling, Bioactive Composition, and Biological Applications of Lepidium sativum L.
AU - Painuli, Sakshi
AU - Quispe, Cristina
AU - Herrera-Bravo, Jesús
AU - Semwal, Prabhakar
AU - Martorell, Miquel
AU - Almarhoon, Zainab M.
AU - Seilkhan, Ainur
AU - Ydyrys, Alibek
AU - Rad, Javad Sharifi
AU - Alshehri, Mohammed M.
AU - Daştan, Sevgi Durna
AU - Taheri, Yasaman
AU - Calina, Daniela
AU - Cho, William C.
N1 - Publisher Copyright:
© 2022 Sakshi Painuli et al.
PY - 2022
Y1 - 2022
N2 - The roots, leaves, and seeds of Lepidium sativum L., popularly known as Garden cress in different regions, have high economic importance; although, the crop is particularly cultivated for the seeds. In traditional medicine, this plant has been reported to possess various biological activities. This review is aimed at providing updated and critical scientific information about the traditional, nutritional, phytochemical, and biological activities of L. sativum. In addition, the geographic distribution is also reviewed. The comprehensive literature search was carried out with the help of different search engines PubMed, Web of Science, and Science Direct. This review highlighted the importance of L. sativum as an edible herb that possesses a wide range of therapeutic properties along with high nutritional values. Preclinical studies (in vitro and in vivo) displayed anticancer, hepatoprotective, antidiabetic, hypoglycemic, antioxidant, antimicrobial, gastrointestinal, and fracture/bone healing activities of L. sativum and support the clinical importance of plant-derived bioactive compounds for the treatment of different diseases. Screening of literature revealed that L. sativum species and their bioactive compounds may be a significant source for new drug compounds and also could be used against malnutrition. Further clinical trials are needed to effectively assess the actual potential of the species and its bioactive compounds.
AB - The roots, leaves, and seeds of Lepidium sativum L., popularly known as Garden cress in different regions, have high economic importance; although, the crop is particularly cultivated for the seeds. In traditional medicine, this plant has been reported to possess various biological activities. This review is aimed at providing updated and critical scientific information about the traditional, nutritional, phytochemical, and biological activities of L. sativum. In addition, the geographic distribution is also reviewed. The comprehensive literature search was carried out with the help of different search engines PubMed, Web of Science, and Science Direct. This review highlighted the importance of L. sativum as an edible herb that possesses a wide range of therapeutic properties along with high nutritional values. Preclinical studies (in vitro and in vivo) displayed anticancer, hepatoprotective, antidiabetic, hypoglycemic, antioxidant, antimicrobial, gastrointestinal, and fracture/bone healing activities of L. sativum and support the clinical importance of plant-derived bioactive compounds for the treatment of different diseases. Screening of literature revealed that L. sativum species and their bioactive compounds may be a significant source for new drug compounds and also could be used against malnutrition. Further clinical trials are needed to effectively assess the actual potential of the species and its bioactive compounds.
UR - https://www.scopus.com/pages/publications/85123905783
U2 - 10.1155/2022/2910411
DO - 10.1155/2022/2910411
M3 - Artículo de revisión
C2 - 35096265
AN - SCOPUS:85123905783
SN - 1942-0900
VL - 2022
JO - Oxidative Medicine and Cellular Longevity
JF - Oxidative Medicine and Cellular Longevity
M1 - 2910411
ER -
