Novel Therapies for Biofilm-Based Candida spp. Infections

Lucia Černáková, Catilin Light, Bahare Salehi, Cristian Rogel-Castillo, Montserrat Victoriano, Miquel Martorell, Javad Sharifi-Rad, Natália Martins, Célia F. Rodrigues

Producción científica: Capítulo del libro/informe/acta de congresoCapítulorevisión exhaustiva

29 Citas (Scopus)

Resumen

The presence of fungal infections continue to grow worldwide, mostly in immunosuppressed patients, and in individuals with continued antimicrobial treatments. Candida spp. are the most common yeasts involved in these disorders, being associated with a high rate of antifungal resistance and an increased ability to form biofilms, which make the treatment of these infections difficult. This review aims to present and discuss the main biofilm-related infections cause by several Candida spp. and novel therapies that are currently available in the clinical, scientific and academic environment. New drugs with promising antifungal activity, natural approaches (e.g. probiotics, essential oils, plant extracts, honey) and a final consideration on alternative methodologies, such as photodynamic therapy are presented and discussed.

Idioma originalInglés
Título de la publicación alojadaAdvances in Experimental Medicine and Biology
EditorialSpringer
Páginas93-123
Número de páginas31
DOI
EstadoPublicada - 2019
Publicado de forma externa

Serie de la publicación

NombreAdvances in Experimental Medicine and Biology
Volumen1214
ISSN (versión impresa)0065-2598
ISSN (versión digital)2214-8019

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