Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

Yasaman Taheri; Hafiz Ansar Rasul Suleria; Natália Martins; Oksana Sytar; Ahmet Beyatli; Balakyz Yeskaliyeva; Gulnaz Seitimova; Bahare Salehi; Prabhakar Semwal; Sakshi Painuli; Anuj Kumar; Elena Azzini; Miquel Martorell; William N. Setzer; Alfred Maroyi; Javad Sharifi-Rad

doi:10.1186/s12906-020-03033-z

Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

Yasaman Taheri
, Hafiz Ansar Rasul Suleria
, Natália Martins
, Oksana Sytar
, Ahmet Beyatli
, Balakyz Yeskaliyeva
, Gulnaz Seitimova
, Bahare Salehi
, Prabhakar Semwal
, Sakshi Painuli
, Anuj Kumar
, Elena Azzini
, Miquel Martorell
, William N. Setzer
, Alfred Maroyi
, Javad Sharifi-Rad

Shahid Beheshti University of Medical Sciences
University of Melbourne
University of Porto
Kyiv National Taras Shevchenko University
Slovak University of Agriculture in Nitra
University of Health Sciences
Al Farabi Kazakh National University
Bam University of Medical Sciences
Graphic Era
Uttarakhand State Council for Science and Technology
Himalayan Environmental Studies and Conservation Organization
Uttarakhand Council for Biotechnology (UCB)
CREA-Research Centre for Food and Nutrition
Universidad de Concepción
University of Alabama in Huntsville
Aromatic Plant Research Center
University of Fort Hare
Zabol University of Medical Sciences

Producción científica: Contribución a una revista › Artículo de revisión › revisión exhaustiva

216 Citas (Scopus)

Resumen

Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.

Idioma original	Inglés
Número de artículo	241
Publicación	BMC Complementary and Alternative Medicine
Volumen	20
N.º	1
DOI	https://doi.org/10.1186/s12906-020-03033-z
Estado	Publicada - 1 ago. 2020
Publicado de forma externa	Sí

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Taheri, Y., Suleria, H. A. R., Martins, N., Sytar, O., Beyatli, A., Yeskaliyeva, B., Seitimova, G., Salehi, B., Semwal, P., Painuli, S., Kumar, A., Azzini, E., Martorell, M., Setzer, W. N., Maroyi, A., & Sharifi-Rad, J. (2020). Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications. BMC Complementary and Alternative Medicine, 20(1), Artículo 241. https://doi.org/10.1186/s12906-020-03033-z

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title = "Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications",

abstract = "Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.",

keywords = "Antimicrobial, Antioxidant, Cancer, Cardiovascular disease, Diabetes, Immunomodulatory, Myricetin, Neuroprotection",

author = "Yasaman Taheri and Suleria, \{Hafiz Ansar Rasul\} and Nat{\'a}lia Martins and Oksana Sytar and Ahmet Beyatli and Balakyz Yeskaliyeva and Gulnaz Seitimova and Bahare Salehi and Prabhakar Semwal and Sakshi Painuli and Anuj Kumar and Elena Azzini and Miquel Martorell and Setzer, \{William N.\} and Alfred Maroyi and Javad Sharifi-Rad",

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month = aug,

day = "1",

doi = "10.1186/s12906-020-03033-z",

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Taheri, Y, Suleria, HAR, Martins, N, Sytar, O, Beyatli, A, Yeskaliyeva, B, Seitimova, G, Salehi, B, Semwal, P, Painuli, S, Kumar, A, Azzini, E, Martorell, M, Setzer, WN, Maroyi, A & Sharifi-Rad, J 2020, 'Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications', BMC Complementary and Alternative Medicine, vol. 20, n.º 1, 241. https://doi.org/10.1186/s12906-020-03033-z

TY - JOUR

T1 - Myricetin bioactive effects

T2 - Moving from preclinical evidence to potential clinical applications

AU - Taheri, Yasaman

AU - Suleria, Hafiz Ansar Rasul

AU - Martins, Natália

AU - Sytar, Oksana

AU - Beyatli, Ahmet

AU - Yeskaliyeva, Balakyz

AU - Seitimova, Gulnaz

AU - Salehi, Bahare

AU - Semwal, Prabhakar

AU - Painuli, Sakshi

AU - Kumar, Anuj

AU - Azzini, Elena

AU - Martorell, Miquel

AU - Setzer, William N.

AU - Maroyi, Alfred

AU - Sharifi-Rad, Javad

PY - 2020/8/1

Y1 - 2020/8/1

N2 - Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.

AB - Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.

KW - Antimicrobial

KW - Antioxidant

KW - Cancer

KW - Cardiovascular disease

KW - Diabetes

KW - Immunomodulatory

KW - Myricetin

KW - Neuroprotection

UR - https://www.scopus.com/pages/publications/85089388182

U2 - 10.1186/s12906-020-03033-z

DO - 10.1186/s12906-020-03033-z

M3 - Artículo de revisión

C2 - 32738903

AN - SCOPUS:85089388182

SN - 1472-6882

VL - 20

JO - BMC Complementary and Alternative Medicine

JF - BMC Complementary and Alternative Medicine

IS - 1

M1 - 241

ER -

Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

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