TY - JOUR
T1 - Myricetin bioactive effects
T2 - Moving from preclinical evidence to potential clinical applications
AU - Taheri, Yasaman
AU - Suleria, Hafiz Ansar Rasul
AU - Martins, Natália
AU - Sytar, Oksana
AU - Beyatli, Ahmet
AU - Yeskaliyeva, Balakyz
AU - Seitimova, Gulnaz
AU - Salehi, Bahare
AU - Semwal, Prabhakar
AU - Painuli, Sakshi
AU - Kumar, Anuj
AU - Azzini, Elena
AU - Martorell, Miquel
AU - Setzer, William N.
AU - Maroyi, Alfred
AU - Sharifi-Rad, Javad
N1 - Publisher Copyright:
© 2020 The Author(s).
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.
AB - Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.
KW - Antimicrobial
KW - Antioxidant
KW - Cancer
KW - Cardiovascular disease
KW - Diabetes
KW - Immunomodulatory
KW - Myricetin
KW - Neuroprotection
UR - https://www.scopus.com/pages/publications/85089388182
U2 - 10.1186/s12906-020-03033-z
DO - 10.1186/s12906-020-03033-z
M3 - Artículo de revisión
C2 - 32738903
AN - SCOPUS:85089388182
SN - 1472-6882
VL - 20
JO - BMC Complementary Medicine and Therapies
JF - BMC Complementary Medicine and Therapies
IS - 1
M1 - 241
ER -
