Disappearing cerebral microbleed after a lacunar infarct

Both, lacunar infarcts and deep cerebral microbleeds are recognized markers of cerebral small vessel disease. However, the "de novo" appearance of an infarct at the site of a previously documented microbleeds has not been described. Here, we report a patient who suffered a lacunar infarct at the site of a microbleed, associated with its disappearing on MRI. This case illustrate a previously unrecognized progression of a cerebral microbleed, which may help to elucidate pathogenetic mechanisms involved in this uncommon evolution.