TY - JOUR
T1 - Development of nasal polyposis post COVID-19 infection
T2 - A case report
AU - Hidalgo-Esparza, Analía
AU - Paredes-Parada, Denisse
AU - Siguencia-Cevallos, Sabrina
AU - Tingo-Granda, Tatiana
AU - Flores-Suárez, Diego
AU - Matamoros-Sotomayor, Antonio
AU - Chérrez-Ojeda, Iván
N1 - Publisher Copyright:
© 2025
PY - 2025/9
Y1 - 2025/9
N2 - Nasal polyposis (NP) is a condition characterized by the growth of benign masses in the nasal cavities, associated with chronic inflammation and edema. Recent studies suggest that viral infections may contribute to the development of NP by triggering Th2-skewed immune responses. This case reports a 61-year-old male who developed nasal polyps following SARS-CoV-2 infection. Despite no history of chronic allergic disease or rhinosinusitis, the patient experienced a dry cough and significant nasal obstruction and rhinorrhea, as well as other symptoms consistent with NP. Treatment with mometasone furoate nasal spray showed symptom improvement and polyp size reduction, confirmed by patient-reported outcome measures (PROMs). This suggests that post-SARS-CoV-2 NP could be part of the complications seen in Long COVID. It highlights the need for further research to understand underlying mechanisms and optimize treatment strategies for Long COVID associated NP.
AB - Nasal polyposis (NP) is a condition characterized by the growth of benign masses in the nasal cavities, associated with chronic inflammation and edema. Recent studies suggest that viral infections may contribute to the development of NP by triggering Th2-skewed immune responses. This case reports a 61-year-old male who developed nasal polyps following SARS-CoV-2 infection. Despite no history of chronic allergic disease or rhinosinusitis, the patient experienced a dry cough and significant nasal obstruction and rhinorrhea, as well as other symptoms consistent with NP. Treatment with mometasone furoate nasal spray showed symptom improvement and polyp size reduction, confirmed by patient-reported outcome measures (PROMs). This suggests that post-SARS-CoV-2 NP could be part of the complications seen in Long COVID. It highlights the need for further research to understand underlying mechanisms and optimize treatment strategies for Long COVID associated NP.
KW - Corticosteroids
KW - Inflammation
KW - Long COVID
KW - Nasal polyps
KW - Patient-reported outcomes
KW - SARS-CoV-2
UR - https://www.scopus.com/pages/publications/105012371493
U2 - 10.1016/j.xocr.2025.100682
DO - 10.1016/j.xocr.2025.100682
M3 - Artículo
AN - SCOPUS:105012371493
SN - 2468-5488
VL - 36
JO - Otolaryngology Case Reports
JF - Otolaryngology Case Reports
M1 - 100682
ER -