TY - JOUR
T1 - Biosensing chips for cancer diagnosis and treatment
T2 - a new wave towards clinical innovation
AU - Iqbal, Muhammad Javed
AU - Javed, Zeeshan
AU - Herrera-Bravo, Jesús
AU - Sadia, Haleema
AU - Anum, Faiza
AU - Raza, Shahid
AU - Tahir, Arifa
AU - Shahwani, Muhammad Naeem
AU - Sharifi-Rad, Javad
AU - Calina, Daniela
AU - Cho, William C.
N1 - Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - Recent technological advances in nanoscience and material designing have led to the development of point-of-care devices for biomolecule sensing and cancer diagnosis. In situ and portable sensing devices for bedside, diagnosis can effectively improve the patient’s clinical outcomes and reduce the mortality rate. Detection of exosomal RNAs by immuno-biochip with increased sensitivity and specificity to diagnose cancer has raised the understanding of the tumor microenvironment and many other technology-based biosensing devices hold great promise for clinical innovations to conquer the unbeatable fort of cancer metastasis. Electrochemical biosensors are the most sensitive category of biomolecule detection sensors with significantly low concentrations down to the atomic level. In this sense, this review addresses the recent advances in cancer detection and diagnosis by developing significant biological sensing devices that are believed to have better sensing potential than existing facilities.
AB - Recent technological advances in nanoscience and material designing have led to the development of point-of-care devices for biomolecule sensing and cancer diagnosis. In situ and portable sensing devices for bedside, diagnosis can effectively improve the patient’s clinical outcomes and reduce the mortality rate. Detection of exosomal RNAs by immuno-biochip with increased sensitivity and specificity to diagnose cancer has raised the understanding of the tumor microenvironment and many other technology-based biosensing devices hold great promise for clinical innovations to conquer the unbeatable fort of cancer metastasis. Electrochemical biosensors are the most sensitive category of biomolecule detection sensors with significantly low concentrations down to the atomic level. In this sense, this review addresses the recent advances in cancer detection and diagnosis by developing significant biological sensing devices that are believed to have better sensing potential than existing facilities.
KW - Biomarkers
KW - Biosensors
KW - Cancer detection
KW - Clinical diagnostics
KW - Diagnostics
KW - Oncogenes
UR - https://www.scopus.com/pages/publications/85141992483
U2 - 10.1186/s12935-022-02777-7
DO - 10.1186/s12935-022-02777-7
M3 - Artículo de revisión
AN - SCOPUS:85141992483
SN - 1475-2867
VL - 22
JO - Cancer Cell International
JF - Cancer Cell International
IS - 1
M1 - 354
ER -
