TY - JOUR
T1 - Apium plants
T2 - Beyond simple food and phytopharmacological applications
AU - Salehi, Bahare
AU - Venditti, Alessandro
AU - Frezza, Claudio
AU - Yücetepe, Aysun
AU - Altuntaş, Ümit
AU - Uluata, Sibel
AU - Butnariu, Monica
AU - Sarac, Ioan
AU - Shaheen, Shabnum
AU - Petropoulos, Spyridon A.
AU - Matthews, Karl R.
AU - Kiliç, Ceyda Sibel
AU - Atanassova, Maria
AU - Adetunji, Charles Oluwaseun
AU - Ademiluyi, Adedayo Oluwaseun
AU - Özçelik, Beraat
AU - Fokou, Patrick Valere Tsouh
AU - Martins, Natália
AU - Cho, William C.
AU - Sharifi-Rad, Javad
N1 - Publisher Copyright:
© 2019 by the authors.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.
AB - Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.
KW - Apium
KW - Botany
KW - Medicinal use
KW - Pharmacological properties
KW - Phytochemicals
UR - https://www.scopus.com/pages/publications/85072296771
U2 - 10.3390/app9173547
DO - 10.3390/app9173547
M3 - Artículo de revisión
AN - SCOPUS:85072296771
SN - 2076-3417
VL - 9
JO - Applied Sciences (Switzerland)
JF - Applied Sciences (Switzerland)
IS - 17
M1 - 3547
ER -
