TY - JOUR
T1 - A Literature-Based Update on Benincasa hispida (Thunb.) Cogn.
T2 - Traditional Uses, Nutraceutical, and Phytopharmacological Profiles
AU - Islam, Muhammad Torequl
AU - Quispe, Cristina
AU - El-Kersh, Dina M.
AU - Shill, Manik Chandra
AU - Bhardwaj, Kanchan
AU - Bhardwaj, Prerna
AU - Sharifi-Rad, Javad
AU - Martorell, Miquel
AU - Hossain, Rajib
AU - Al-Harrasi, Ahmed
AU - Al-Rawahi, Ahmed
AU - Butnariu, Monica
AU - Rotariu, Lia Sanda
AU - Suleria, Hafiz Ansar Rasul
AU - Taheri, Yasaman
AU - Docea, Anca Oana
AU - Calina, Daniela
AU - Cho, William C.
N1 - Publisher Copyright:
© 2021 Muhammad Torequl Islam et al.
PY - 2021
Y1 - 2021
N2 - Benincasa hispida (Thunb.) Cogn. (Cucurbitaceae) is an annual climbing plant, native to Asia with multiple therapeutic uses in traditional medicine. This updated review is aimed at discussing the ethnopharmacological, phytochemical, pharmacological properties, and molecular mechanisms highlighted in preclinical experimental studies and toxicological safety to evaluate the therapeutic potential of this genus. The literature from PubMed, Google Scholar, Elsevier, Springer, Science Direct, and database was analyzed using the basic keyword "Benincasa hispida."Other searching strategies, including online resources, books, and journals, were used. The taxonomy of the plant has been made by consulting "The Plant List". The results showed that B. hispida has been used in traditional medicine to treat neurological diseases, kidney disease, fever, and cough accompanied by thick mucus and to fight intestinal worms. The main bioactive compounds contained in Benincasa hispida have cytotoxic, anti-inflammatory, and anticancer properties. Further safety and efficacy investigations are needed to confirm these beneficial therapeutic effects and also future human clinical studies.
AB - Benincasa hispida (Thunb.) Cogn. (Cucurbitaceae) is an annual climbing plant, native to Asia with multiple therapeutic uses in traditional medicine. This updated review is aimed at discussing the ethnopharmacological, phytochemical, pharmacological properties, and molecular mechanisms highlighted in preclinical experimental studies and toxicological safety to evaluate the therapeutic potential of this genus. The literature from PubMed, Google Scholar, Elsevier, Springer, Science Direct, and database was analyzed using the basic keyword "Benincasa hispida."Other searching strategies, including online resources, books, and journals, were used. The taxonomy of the plant has been made by consulting "The Plant List". The results showed that B. hispida has been used in traditional medicine to treat neurological diseases, kidney disease, fever, and cough accompanied by thick mucus and to fight intestinal worms. The main bioactive compounds contained in Benincasa hispida have cytotoxic, anti-inflammatory, and anticancer properties. Further safety and efficacy investigations are needed to confirm these beneficial therapeutic effects and also future human clinical studies.
UR - https://www.scopus.com/pages/publications/85122260102
U2 - 10.1155/2021/6349041
DO - 10.1155/2021/6349041
M3 - Artículo de revisión
C2 - 34925698
AN - SCOPUS:85122260102
SN - 1942-0900
VL - 2021
JO - Oxidative Medicine and Cellular Longevity
JF - Oxidative Medicine and Cellular Longevity
M1 - 6349041
ER -
