TY - JOUR
T1 - Therapeutic potential of cranberry for kidney health and diseases
AU - Amin, Ruhul
AU - Thalluri, Chandrashekar
AU - Docea, Anca Oana
AU - Sharifi-Rad, Javad
AU - Calina, Daniela
N1 - Publisher Copyright:
© 2022 The Authors. eFood published by John Wiley & Sons Australia, Ltd on behalf of International Association of Dietetic Nutrition and Safety.
PY - 2022/10
Y1 - 2022/10
N2 - A higher risk of cardiovascular mortality in persons with chronic renal failure (CRF) is linked to inflammation, oxidative stress, cellular aging, and gut dysbiosis, to name a few contributing factors. According to a growing body of evidence, some dietary choices may reduce the severity of certain adverse effects. Specialized databases such as PubMed/Medline, Embase, Google Scholar, and UpToDate were searched to find published studies that focus on the pharmacological effects and mechanisms of cranberries’ bioactive compounds on CRF and human health. Cranberry supplementation has been demonstrated in clinical research to offer health advantages for humans, such as reducing urinary tract infections. Recently, it has been reported that cranberry polyphenols possess anti-inflammatory and antioxidant effects and are also known to have the capacity to affect gut flora. Scientific studies on the beneficial pharmacological effects of cranberries on human health may provide an understanding of traditional cranberry therapy in chronic kidney disease and other chronic conditions. However, translational studies are needed to determine the exact dose that can be administered to humans as well as the validation of nutritional supplements that contain cranberry extract.
AB - A higher risk of cardiovascular mortality in persons with chronic renal failure (CRF) is linked to inflammation, oxidative stress, cellular aging, and gut dysbiosis, to name a few contributing factors. According to a growing body of evidence, some dietary choices may reduce the severity of certain adverse effects. Specialized databases such as PubMed/Medline, Embase, Google Scholar, and UpToDate were searched to find published studies that focus on the pharmacological effects and mechanisms of cranberries’ bioactive compounds on CRF and human health. Cranberry supplementation has been demonstrated in clinical research to offer health advantages for humans, such as reducing urinary tract infections. Recently, it has been reported that cranberry polyphenols possess anti-inflammatory and antioxidant effects and are also known to have the capacity to affect gut flora. Scientific studies on the beneficial pharmacological effects of cranberries on human health may provide an understanding of traditional cranberry therapy in chronic kidney disease and other chronic conditions. However, translational studies are needed to determine the exact dose that can be administered to humans as well as the validation of nutritional supplements that contain cranberry extract.
KW - catechin
KW - chronic renal failure
KW - cranberries
KW - human health
KW - procianidins
UR - https://www.scopus.com/pages/publications/85139961684
U2 - 10.1002/efd2.33
DO - 10.1002/efd2.33
M3 - Artículo de revisión
AN - SCOPUS:85139961684
SN - 2666-3066
VL - 3
JO - eFood
JF - eFood
IS - 5
M1 - e33
ER -
