Potency of inhibitors depends upon the accessibility of their aromatic rings within the hydrophobic specificity pocket: a novel avenue for future aldose reductase inhibitor design

Saif Khan; Pallavi Somvanshi; Aditi Singh; Mahvish Khan; Raju K. Mandal; Sajad A. Dar; Mohd Wahid; Arshad Jawed; Bhartendu Nath Mishra; Shafiul Haque

doi:10.1080/07391102.2020.1733090

Potency of inhibitors depends upon the accessibility of their aromatic rings within the hydrophobic specificity pocket: a novel avenue for future aldose reductase inhibitor design

Saif Khan
, Pallavi Somvanshi
, Aditi Singh
, Mahvish Khan
, Raju K. Mandal
, Sajad A. Dar
, Mohd Wahid
, Arshad Jawed
, Bhartendu Nath Mishra
, Shafiul Haque

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

Abstract

Communicated by Ramaswamy H. Sarma.

Original language	English
Pages (from-to)	1512-1518
Number of pages	7
Journal	Journal of Biomolecular Structure and Dynamics
Volume	39
Issue number	4
DOIs	https://doi.org/10.1080/07391102.2020.1733090
State	Published - 2021
Externally published	Yes

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10.1080/07391102.2020.1733090

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Khan, S., Somvanshi, P., Singh, A., Khan, M., Mandal, R. K., Dar, S. A., Wahid, M., Jawed, A., Mishra, B. N., & Haque, S. (2021). Potency of inhibitors depends upon the accessibility of their aromatic rings within the hydrophobic specificity pocket: a novel avenue for future aldose reductase inhibitor design. Journal of Biomolecular Structure and Dynamics, 39(4), 1512-1518. https://doi.org/10.1080/07391102.2020.1733090

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title = "Potency of inhibitors depends upon the accessibility of their aromatic rings within the hydrophobic specificity pocket: a novel avenue for future aldose reductase inhibitor design",

abstract = "Communicated by Ramaswamy H. Sarma.",

author = "Saif Khan and Pallavi Somvanshi and Aditi Singh and Mahvish Khan and Mandal, \{Raju K.\} and Dar, \{Sajad A.\} and Mohd Wahid and Arshad Jawed and Mishra, \{Bhartendu Nath\} and Shafiul Haque",

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year = "2021",

doi = "10.1080/07391102.2020.1733090",

language = "Ingl{\'e}s",

volume = "39",

pages = "1512--1518",

journal = "Journal of Biomolecular Structure and Dynamics",

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Khan, S, Somvanshi, P, Singh, A, Khan, M, Mandal, RK, Dar, SA, Wahid, M, Jawed, A, Mishra, BN & Haque, S 2021, 'Potency of inhibitors depends upon the accessibility of their aromatic rings within the hydrophobic specificity pocket: a novel avenue for future aldose reductase inhibitor design', Journal of Biomolecular Structure and Dynamics, vol. 39, no. 4, pp. 1512-1518. https://doi.org/10.1080/07391102.2020.1733090

Potency of inhibitors depends upon the accessibility of their aromatic rings within the hydrophobic specificity pocket: a novel avenue for future aldose reductase inhibitor design. / Khan, Saif; Somvanshi, Pallavi; Singh, Aditi et al.
In: Journal of Biomolecular Structure and Dynamics, Vol. 39, No. 4, 2021, p. 1512-1518.

Research output: Contribution to journal › Letter › peer-review

TY - JOUR

T1 - Potency of inhibitors depends upon the accessibility of their aromatic rings within the hydrophobic specificity pocket

T2 - a novel avenue for future aldose reductase inhibitor design

AU - Khan, Saif

AU - Somvanshi, Pallavi

AU - Singh, Aditi

AU - Khan, Mahvish

AU - Mandal, Raju K.

AU - Dar, Sajad A.

AU - Wahid, Mohd

AU - Jawed, Arshad

AU - Mishra, Bhartendu Nath

AU - Haque, Shafiul

PY - 2021

Y1 - 2021

N2 - Communicated by Ramaswamy H. Sarma.

AB - Communicated by Ramaswamy H. Sarma.

UR - https://www.scopus.com/pages/publications/85081330351

U2 - 10.1080/07391102.2020.1733090

DO - 10.1080/07391102.2020.1733090

M3 - Carta

C2 - 32081090

AN - SCOPUS:85081330351

SN - 0739-1102

VL - 39

SP - 1512

EP - 1518

JO - Journal of Biomolecular Structure and Dynamics

JF - Journal of Biomolecular Structure and Dynamics

IS - 4

ER -

Potency of inhibitors depends upon the accessibility of their aromatic rings within the hydrophobic specificity pocket: a novel avenue for future aldose reductase inhibitor design

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