LncRNAs as potential therapeutic targets in thyroid cancer

Zeeshan Javed; Faiez Ahmed Shah; Sadegh Rajabi; Qamar Raza; Zaheer Iqbal; Mukhtar Ullah; Touqeer Ahmad; Bahare Salehi; Mehdi Sharifi-Rad; Raffaele Pezzani; Farooq Yaqoob; Haleema Sadia; Marcello Iriti; Javad Sharifi-Rad; William C. Cho

doi:10.31557/APJCP.2020.21.2.281

LncRNAs as potential therapeutic targets in thyroid cancer

Zeeshan Javed
, Faiez Ahmed Shah
, Sadegh Rajabi
, Qamar Raza
, Zaheer Iqbal
, Mukhtar Ullah
, Touqeer Ahmad
, Bahare Salehi
, Mehdi Sharifi-Rad
, Raffaele Pezzani
, Farooq Yaqoob
, Haleema Sadia
, Marcello Iriti
, Javad Sharifi-Rad
, William C. Cho

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Abstract

Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology.

Original language	English
Pages (from-to)	281-287
Number of pages	7
Journal	Asian Pacific Journal of Cancer Prevention
Issue number	2
DOIs	https://doi.org/10.31557/APJCP.2020.21.2.281
State	Published - 2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Genetic alterations
LncRNA
Thyroid cancer
Treatment

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10.31557/APJCP.2020.21.2.281

Cite this

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title = "LncRNAs as potential therapeutic targets in thyroid cancer",

abstract = "Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology.",

keywords = "Genetic alterations, LncRNA, Thyroid cancer, Treatment",

author = "Zeeshan Javed and Shah, \{Faiez Ahmed\} and Sadegh Rajabi and Qamar Raza and Zaheer Iqbal and Mukhtar Ullah and Touqeer Ahmad and Bahare Salehi and Mehdi Sharifi-Rad and Raffaele Pezzani and Farooq Yaqoob and Haleema Sadia and Marcello Iriti and Javad Sharifi-Rad and Cho, \{William C.\}",

note = "Publisher Copyright: {\textcopyright} 2020 Asian Pacific Organization for Cancer Prevention.",

year = "2020",

doi = "10.31557/APJCP.2020.21.2.281",

language = "Ingl{\'e}s",

pages = "281--287",

journal = "Asian Pacific Journal of Cancer Prevention",

issn = "1513-7368",

publisher = "Asian Pacific Organization for Cancer Prevention",

number = "2",

}

TY - JOUR

T1 - LncRNAs as potential therapeutic targets in thyroid cancer

AU - Javed, Zeeshan

AU - Shah, Faiez Ahmed

AU - Rajabi, Sadegh

AU - Raza, Qamar

AU - Iqbal, Zaheer

AU - Ullah, Mukhtar

AU - Ahmad, Touqeer

AU - Salehi, Bahare

AU - Sharifi-Rad, Mehdi

AU - Pezzani, Raffaele

AU - Yaqoob, Farooq

AU - Sadia, Haleema

AU - Iriti, Marcello

AU - Sharifi-Rad, Javad

AU - Cho, William C.

PY - 2020

Y1 - 2020

N2 - Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology.

AB - Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology.

KW - Genetic alterations

KW - LncRNA

KW - Thyroid cancer

KW - Treatment

UR - https://www.scopus.com/pages/publications/85080151558

U2 - 10.31557/APJCP.2020.21.2.281

DO - 10.31557/APJCP.2020.21.2.281

M3 - Artículo de revisión

C2 - 32102500

AN - SCOPUS:85080151558

SN - 1513-7368

SP - 281

EP - 287

JO - Asian Pacific Journal of Cancer Prevention

JF - Asian Pacific Journal of Cancer Prevention

IS - 2

ER -

LncRNAs as potential therapeutic targets in thyroid cancer

Abstract

UN SDGs

Keywords

Access to Document

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