Desmodium adscendens (Sw.) DC. A magnificent plant with biological and pharmacological properties

  • Maria Giulia Manzione
  • , Jesús Herrera-Bravo
  • , Javad Sharifi-Rad
  • , Dorota Kregiel
  • , Mustafa Sevindik
  • , Emre Sevindik
  • , Zeliha Salamoglu
  • , Wissam Zam
  • , Sara Vitalini
  • , Christophe Hano
  • , Wirginia Kukula-Koch
  • , Wojciech Koch
  • , Raffaele Pezzani

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Desmodium adscendens (Sw.) DC. is a plant of the Fabaceae family especially rich in flavonoids but also in alkaloids, terpenoids, steroids, phenols, phenylpropanoids, glycosides, and volatiles. This herb has been traditionally used in numerous countries all over the world for its pharmacological and biological properties (i.e., it has been used for the treatment of diarrheas, fever, epilepsy, asthma, leishmaniasis, gastroduodenal ulcer, diabetes, hepatic diseases, etc.). Given the wide uses of D. adscendens, this review summarizes all recent data on D. adscendens evaluating its phytochemistry as well as its ethno-traditional and pharmacological properties. In addition, an association between the phytocompounds of this plant and its potential mechanism of action in cell and animal models has been investigated, focusing with a special emphasis on human experiments.

Original languageEnglish
Pages (from-to)677-688
Number of pages12
JournalFood Frontiers
Volume3
Issue number4
DOIs
StatePublished - Dec 2022
Externally publishedYes

Keywords

  • Desmodium adscendens
  • clinical trial
  • pharmacological properties
  • phytochemistry
  • preclinical studies

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