Antiulcer agents: From plant extracts to phytochemicals in healing promotion

Mehdi Sharifi-Rad; Patrick Valere Tsouh Fokou; Farukh Sharopov; Miquel Martorell; Adedayo Oluwaseun Ademiluyi; Jovana Rajkovic; Bahare Salehi; Natália Martins; Marcello Iriti; Javad Sharifi-Rad

doi:10.3390/molecules23071751

Antiulcer agents: From plant extracts to phytochemicals in healing promotion

Mehdi Sharifi-Rad
, Patrick Valere Tsouh Fokou
, Farukh Sharopov
, Miquel Martorell
, Adedayo Oluwaseun Ademiluyi
, Jovana Rajkovic
, Bahare Salehi
, Natália Martins
, Marcello Iriti
, Javad Sharifi-Rad

Research output: Contribution to journal › Review article › peer-review

179 Scopus citations

Abstract

In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.

Original language	English
Article number	1751
Journal	Molecules
Volume	23
Issue number	7
DOIs	https://doi.org/10.3390/molecules23071751
State	Published - 2018
Externally published	Yes

Keywords

Bioactive phytochemicals
Gastric cancer
Helicobacter pylori
Herbal remedies
Peptic ulcer
Traditional healing systems

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/molecules23071751

Cite this

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title = "Antiulcer agents: From plant extracts to phytochemicals in healing promotion",

abstract = "In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.",

keywords = "Bioactive phytochemicals, Gastric cancer, Helicobacter pylori, Herbal remedies, Peptic ulcer, Traditional healing systems",

author = "Mehdi Sharifi-Rad and Fokou, \{Patrick Valere Tsouh\} and Farukh Sharopov and Miquel Martorell and Ademiluyi, \{Adedayo Oluwaseun\} and Jovana Rajkovic and Bahare Salehi and Nat{\'a}lia Martins and Marcello Iriti and Javad Sharifi-Rad",

note = "Publisher Copyright: {\textcopyright} 2018 by the authors.",

year = "2018",

doi = "10.3390/molecules23071751",

language = "Ingl{\'e}s",

volume = "23",

journal = "Molecules",

issn = "1420-3049",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "7",

}

TY - JOUR

T1 - Antiulcer agents

T2 - From plant extracts to phytochemicals in healing promotion

AU - Sharifi-Rad, Mehdi

AU - Fokou, Patrick Valere Tsouh

AU - Sharopov, Farukh

AU - Martorell, Miquel

AU - Ademiluyi, Adedayo Oluwaseun

AU - Rajkovic, Jovana

AU - Salehi, Bahare

AU - Martins, Natália

AU - Iriti, Marcello

AU - Sharifi-Rad, Javad

PY - 2018

Y1 - 2018

N2 - In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.

AB - In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.

KW - Bioactive phytochemicals

KW - Gastric cancer

KW - Helicobacter pylori

KW - Herbal remedies

KW - Peptic ulcer

KW - Traditional healing systems

UR - https://www.scopus.com/pages/publications/85052131237

U2 - 10.3390/molecules23071751

DO - 10.3390/molecules23071751

M3 - Artículo de revisión

C2 - 30018251

AN - SCOPUS:85052131237

SN - 1420-3049

VL - 23

JO - Molecules

JF - Molecules

IS - 7

M1 - 1751

ER -

Antiulcer agents: From plant extracts to phytochemicals in healing promotion

Abstract

Keywords

UN SDGs

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