A Perspective on Emerging Therapeutic Interventions for COVID-19

Muhammad Torequl Islam; Md Nasiruddin; Ishaq N. Khan; Siddhartha Kumar Mishra; Md Kudrat-E-Zahan; Thoufiqul Alam Riaz; Eunus S. Ali; M. Safiur Rahman; Mohammad S. Mubarak; Miquel Martorell; William C. Cho; Daniela Calina; Anca Oana Docea; Javad Sharifi-Rad

doi:10.3389/fpubh.2020.00281

A Perspective on Emerging Therapeutic Interventions for COVID-19

Muhammad Torequl Islam
, Md Nasiruddin
, Ishaq N. Khan
, Siddhartha Kumar Mishra
, Md Kudrat-E-Zahan
, Thoufiqul Alam Riaz
, Eunus S. Ali
, M. Safiur Rahman
, Mohammad S. Mubarak
, Miquel Martorell
, William C. Cho
, Daniela Calina
, Anca Oana Docea
, Javad Sharifi-Rad

Bangabandhu Sheikh Mujibur Rahman Science and Technology University
Khyber Medical University
Dr. Harisingh Gour University, Sagar
Rajshahi University
Jeonbuk National University
Northwestern University
Bangladesh Atomic Energy Commission
University of Jordan
Universidad de Concepción
Queen Elizabeth Hospital Hong Kong
Craiova University of Medicine and Pharmacy
Shahid Beheshti University of Medical Sciences

Research output: Contribution to journal › Review article › peer-review

54 Scopus citations

Abstract

Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.

Original language	English
Article number	281
Journal	Frontiers in Public Health
Volume	8
DOIs	https://doi.org/10.3389/fpubh.2020.00281
State	Published - 3 Jul 2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19 pandemic
SARS-CoV-2
control
public health
therapeutics

Access to Document

10.3389/fpubh.2020.00281

Cite this

Torequl Islam, M., Nasiruddin, M., Khan, I. N., Mishra, S. K., Kudrat-E-Zahan, M., Alam Riaz, T., Ali, E. S., Rahman, M. S., Mubarak, M. S., Martorell, M., Cho, W. C., Calina, D., Docea, A. O., & Sharifi-Rad, J. (2020). A Perspective on Emerging Therapeutic Interventions for COVID-19. Frontiers in Public Health, 8, Article 281. https://doi.org/10.3389/fpubh.2020.00281

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AU - Alam Riaz, Thoufiqul

AU - Ali, Eunus S.

AU - Rahman, M. Safiur

AU - Mubarak, Mohammad S.

AU - Martorell, Miquel

AU - Cho, William C.

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AB - Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.

KW - COVID-19 pandemic

KW - SARS-CoV-2

KW - control

KW - public health

KW - therapeutics

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M3 - Artículo de revisión

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SN - 2296-2565

VL - 8

JO - Frontiers in Public Health

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M1 - 281

ER -

A Perspective on Emerging Therapeutic Interventions for COVID-19

Abstract

UN SDGs

Keywords

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